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Word from the director of the QRHN

The COVID-19 pandemic imposes on us short reaction times which research is not familiar with. Members of the Quebec Respiratory Health Research Network combine their efforts with the Infectious Diseases Network and multiple teams of researchers in Quebec, Canada and internationally to acquire scientific knowledge and develop the necessary innovations in the short, medium and long term for the management of subjects infected with COVID-19. This page aims to publicize the initiatives in which the RSRQ participates and to facilitate researchers' interactions with each other and with clinicians.

Phillipe Jouvet, MD
Director of the QRHN

Evolution of the pandemic

COVID-19 pandemic - Evolution of the number of hospitalizations in progress linked to COVID-19 in Quebec according to the type of stay

Source: INSPQ

Resources

Impact of COVID-19 on the scientific activities of QRHN members

View the survey conducted in January with our regular members to determine what impact COVID-19 has had on their research activities.

Research projects

Title of the projectObjectiveOrigin of fundingCoordinatorQRNH responsible personLink
Provincial BiobankCollecter des échantillons biologiques de sujets infectés par le COVID-19FRQS -MEIVincent MooserSimon RousseauQuebec respiratory health reserach network Biobank
SPRINT SARI COVID-19Collecter les données cliniques codées sur les sujets hospitalisés pour infection à COVID-19CIHRSrinivas Murthy
Rob Fowler
Philippe JouvetSPRINT SARI COVID-19
CATCOEssai clinique randomisé d’une thérapeutique antivirale chez les sujets hospitalisés pour infection à COVID-19CIHRSrinivas MurthyJulie AutmizguineCATCO.pdf
COVID 19 et aérosolisation virale en milieu cliniqueÉtude de la présence des particules virales dans l’environnement immédiat des sujets hospitalisés pour infection par COVID-19FRQSCaroline DuchaineCaroline DuchaineCOVID-19 et Aérosolisation virale hospitalière


https://pubmed.ncbi.nlm.nih.gov/33115724/
XS Zhang, C Duchaine. SARS-CoV-2 and Health Care Worker Protection in Low-Risk Settings: a Review of Modes of Transmission and a Novel Airborne Model Involving Inhalable Particles. Clin Microbiol Rev 2021;34: e00184-20.


https://pubmed.ncbi.nlm.nih.gov/33206022/
N Dumont-Leblond, M Veillette, S Mubareka, L Yip, Y Longtin, P Jouvet, B Paquet Bolduc, S Godbout, G Kobinger, A McGeer, A Mikszewski, C Duchaine. Low incidence of airborne SARS-CoV-2 in acute care hospital rooms with optimized ventilation. Emerg Microbes Infect 2020;9:2597-2605.
PARE-PARTOUX / SplashGuard CGCréer un système de protection des soignants vis à vis des particules virales aérolisées par les sujets hospitalisés pour infection à COVID 19Institut TransMedTechPhilippe JouvetPhilippe JouvetPARE-PARTOUX / SplashGuard CG


https://pubmed.ncbi.nlm.nih.gov/33381311/
François T, Tabone L, Levy A, Seguin LA, Touré T, Aubin CE, Jouvet P. Simulation-Based Rapid Development and Implementation of a Novel Barrier Enclosure for Use in COVID-19 Patients: The SplashGuard CG.
Crit Care Res Pract. 2020;2020:3842506.


https://pubmed.ncbi.nlm.nih.gov/33380356/
Buyck M, Levy A, Tabone L, Aubin CE, Jouvet P, Baudin F. Pediatric barrier enclosure for nasopharyngeal suctioning during Covid-19 pandemic: A simulation based-study. Am J Emerg Med 2020; Online ahead of print.


https://pubmed.ncbi.nlm.nih.gov/33134935/
Idei M, Nomura T, Jouvet P, Aubin CE, Kawaguchi A, Nakagawa M. Video Laryngoscope Intubation With an Aerosol Barrier Device: A Randomized Sequential Crossover Pilot Study. Crit Care Explor 2020;2:e0234.
CODA 19CODA-19: a Collaborative Data Analysis Platform to Improve Clinical Care in Patients with COVID-19CIHRMichael ChasséMichael Sauthierhttps://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=430127&lang=en

Frequencer-COVID 19Comparaison de deux méthodes pour dégager les voies aériennes d’enfant et d’adultes admis aux soins intensifs pour une infection par le COVID-19 : étude pilote.Ministère de l’Économie et de l’Innovation (MEI) et Dymedso IncPhilippe JouvetPhilippe Jouvethttps://pubmed.ncbi.nlm.nih.gov/32620174/


Kawaguchi A, Bernier G, Lacroix J, El Salti S, Cheng MP, Lee TC, Khwaja K, Jouvet P. Comparison of two methods to clear the airways of critically ill children and adults with COVID-19 infection: a structured summary of a study protocol for a pilot randomized controlled trial. Trials 2020;21:610.
TVL COVID 19Tableau numérique de visualisation en soins intensifs de la COVID-19Institut de Valorisation des Données (IVADO) et Institut TransMedTechPhilippe Doyon-PoulinPhilippe Jouvethttps://www.polymtl.ca/carrefour-actualite/nouvelles/covid-19-une-equipe-de-polytechnique-vient-en-aide-lunite-des-soins-intensifs-pediatriques-du-chu
COVID 19 Biomolecular signatureCharacterisation of the Biomolecular Signature of COVID-19 in Human Adult and Children Blood through Label-free Raman Spectroscopy.Conseil de recherches en sciences naturelles et en génie du CanadaM DehaesPhilippe JouvetCOVID_19_Biomolecular_signature.pdf

Understanding the pathogenesis of COVID-19 by defining its lipidomePI: Louis Flamand CO-PI : Nicolas Flamand, Éric Boilard, Marc PouliotNicolas Flamand
PROVID-19Évaluation de l'efficacité des probiotiques sur la réduction de la durée et des symptômes de la COVID-19Centre de recherche du CHU de SherbrookeDr Jean-Charles PasquierDr André Cantinhttp://www.provid-19.ca

Identification d’un profil génétique et microbien de risque pour la COVID-19FCICatherine Laprise CO-PI: Catherine Girard, Guillaume Jourdan, Luigi BouchardCatherine LapriseLien web

Covid-19 Ozanimod Intervention Study (COZI)The primary objective is to substantiate the impact of ozanimod on key outcomes of COVID-19 patient progression, which will guide decision making around sample size and the choice of endpoints for future clinical trialBristol Myers SquibbPascale Blais LecoursDavid Marsolais, François LelloucheLien web

iCARERelier les données comportementales issues des questionnaires aux données sur les mesures, la mobilité et les cas afin de fournir aux gouvernements des recommandations fondées sur des données comportementales probantes quant à la façon d’optimiser les mesures actuelles pour réduire l’impact de la pandémie de COVID-19 au Canada et dans le monde. IRSC, FRQ-Santé, FRQ-Société et culture Kim Lavoie, Simon Bacon et collaborateurs nationaux et internationaux Kim Lavoie, Simon Bacon Lien web

SARS-CoV-2 infection during pulmonary exacerbations in children and adults with cystic fibrosis from the province of Quebec, CanadaRSRQAna BlanchardLien web

The impact of SARS-CoV-2 infection and other pandemic-related measures on asthma and COPD controlRSRQSze Man TseLien web

Impact of prior corticosteroids therapy for airway diseases on COVID-19 clinical trajectoryRSRQSimon RousseauLien web